1. Update the map of data set with Build37 Shifman genetic map and save the new file as "Guay-Woodfor2000_BALBxCAST_B37_Data.csv". The file is ready to be input into Rqtl; 2. Generate a description file of the project, it includes the general information, definitions of phenotypes, description of genotypes and information of missing markers; 3. For the genotypes of this cross: (cM=centimorgan, bp=basepair) (1) Change the genotype symbol from "0" (allele of CAST in original data) to "C", "1" (heterozygous allele in original data) to "H", "2" (allele of BALB in original data) to "B". Change the undefined symbols ("=", "*", "U", " ") to "-" (all the undefined genotype symbols in original data are treated as missing values). This is the standard format in data sets of QTL archive and the changes are saved in B37 data file; (2) Nine markers miss their bp positions in Shifman genetic map, assign the positions from current MGI database. This type of markers are highlighted with orange color and please see description file for details; (3) Marker "D19MIT6" misses bp position in both Shifman map and MGI database. Primer sequences found in MGI, and their locations identified using primer-BLAST in NCBI followed by UCSC In-Silico PCR (it is highlighted with green color in description file); (4) Marker "D7MIT1" misses both cM and bp position in Shifman map. Primer sequences found in MGI, but their locations don't match the result from primer-BLAST in NCBI. Use the interpolating algorithm to calculate the B37 cM position in B37 data file, the bp information is unavailable (it is highlighted with grey color in description file); (5) Unable to find any information of marker "D8MIT1" in Shifman map, find its bp from MGI, then convert it to cM through Map Converter tool (it is highlighted with yellow color in description file); (6) Marker "D8MIT14" misses bp position in both Shifman map and MGI database. Primer sequences found in MGI, but their locations don't match the result from primer-BLAST in NCBI. We could not identify the B37 bp position of this marker currently (these markers are highlighted with pink color in description file); (7) Marker "D12MIT14" misses bp position in both Shifman map and MGI database. Primer sequences found in MGI, but we could not find their locations from primer-BLAST in NCBI. We could not identify the B37 bp position of this marker currently (it is highlighted with brown color in description file); (8) Marker "D11MIT17", "D12MIT21", "D14MIT22" and "D17MIT12" don't have cM positions in the original data set we have, they don't exist in Shifman map and MGI database, either. We use the functions in Rqtl to estimate their approximate cM positions in original file, then use the interpolating algorithm to calculate its new cM position in B37 data file, the bp information are unavailable (the letters of these markers are highlighted by red color in description file); (9) The original data has two "D13MIT20" markers in chr 13 (the 1st and the 3rd marker in this chromosome), but the genotypes of them are different. Based on their cM positions. we treat the 1st marker as a different marker and rename it as "D13MIT20a". We use the functions in Rqtl to estimate its approximate cM position in original file, but the interpolating algorithm doesn't work for this marker, so we set the position of the marker as 1 cM for this cross in B37 data file, the bp information is unavailable; (10) Even after update the genetic map, we notice there is a problem in the markers of chr 11 from the genotype diagnostic plots. The 1st marker "D11MIT1" on chromosome 11 is dropped from B37 data file (suggested by Gary in 11/11/2010); (11) This project doesn't have X-chromosome; 4. For the phenotypes of the cross: (1) Don't find the information of intervention (type of diet) in the paper (highlight in blue color); (2) The original data file doesn't have the information of paternal grandma (pgm); (3) The project only has female mice. Change the symbol from "F" to "0" of sex in B37 data file; 5. Except the "csv" file mentioned above, save the description file, original data, data with B37 map, data process record and missing marker list together as a big excel file ("Data_Description_BALBxCAST_Guay-Woodfor2000.xlsx"). (first curating work finished at 5/26/2009, files updated on 11/3/, 11/16/2010) 6. Information updated on 10/25/2011: (1) Change the name of the map (from "Shifman" to "Cox" map) in description and readme file, add a map reference in description file; (2) Generate genetic map plot, missing genotypes plot, map comparison plot, whole genome RF plot and problematic chromosome RF plots for B37 data. The 2nd marker on chr 11 had marker order problem. Problematic markers were also found on chr 14 (observed from map comparison plot) in this cross. All quality control plots were saved in "QCReport_Guay-Woodford2000.pdf".