1. This paper included two crosses --- BxA f2 intercross and AxB Apoe KO intercross. Updated the map with Build37 Cox genetic map and saved the new files as "Doorenbos2008a_BxA_B37_Data.csv" and "Doorenbos2008b_AxBApoe_B37_Data.csv". The files are ready to be input into Rqtl. This is the readme file of BxA intercross;


2. Generate a description file of the project, it includes the general information, definitions of phenotypes, description of genotypes and information of missing markers;


3. The cross file only had 383 male mice and phenotypes of one mouse was completely missing;


4. For the genotypes of BxA cross (cM=centiMorgan, bp=basepair), the cross has a complete new map (cM) of genetic markers in updating data file; 


5. For the phenotypes:
(1) Could not find the exact definition of trait "Microalb" in paper, assigned the definition of it based on trait name (it is highlighted in blue color followed by "?")

(2) Don't find exact age of mice in the paper, it only mentioned that "Spot urine samples were taken between 8 and 10 weeks", so I used "8~10 weeks" to indicate the mouse age at testing. In addition, I noticed there was a minor conflict between this data set and publication. In the "MATERIALS AND METHODS" section of the paper, the author mentioned that "A/J females were mated to B6 (cross 1) or B6-Apoe KO (cross 2) males to produce the F1 progeny", actually, the direction of the cross1 is (B6xA)F1 x (B6xA)F1; 


6. Except the "csv" files mentioned above, save the description file, original data, data with B37 map, and my data process and missing marker list together as a big excel file "Data_Description_BxA_Doorenbos2008a.xlsx". (1st curation work is done at 5/20/2009, updating files on 7/1/2009, 8/5, 10/26/2010); 


7. Divide the project into 2 projects (Doorenbos2008a and Doorenbos2008b) , one per cross in QTL archive database on 9/17/2010.


8. Information updated on 10/13/2011: 
(1) Change the name of the map (from "Shifman" to "Cox" map) in description and readme file, add a map reference in description file; 

(2) Generate genetic map plot, missing genotypes plot, map comparison plot, whole genome RF plot and problematic chromosome RF plots for B37 data. The last marker on chr 1 might have marker order problem. All quality control plots were saved in "QCReport_Doorenbos2008a.pdf".